Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 may be useful in the treatment of patients with thrombocytopenia. Avatrombopag was first approved in 2018.
Molekulargewicht:
765.72
CAS Nummer:
[677007-74-8]
Formel:
C33H38Cl2N6O7S2
Target-Kategorie:
Others|||Thrombopoietin Receptor
T68888
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