Fenobam hydrate is a noncompetitive antagonist and inverse agonist of metabotropic glutamate receptor 5 (mGluR5). It inhibits intracellular calcium mobilization induced by the glutamate analog quisqualate and inhibits basal activity of mGluR5. Fenobam reduces stress-induced hyperthermia, exhibits anxiolytic-like activity, and may induce analgesia.
Molekulargewicht:
284.7
CAS Nummer:
[63540-28-3]
Formel:
C11H13ClN4O3
Target-Kategorie:
Apoptosis|||Others|||GluR
T68959
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