CJ-463 is a potent ans selective uPA inhibitor. Treatment with CJ-463 resulted in a significant inhibition of primary tumor growth, with the highest efficacy seen in the 100 mg/kg group. Urokinase (uPA) plays a crucial role in carcinogenesis by facilitating tumor cell invasion and metastasis. CJ-463 may be a novel agent for treatment of lung cancer.
Molekulargewicht:
477.53
CAS Nummer:
[600142-19-6]
Formel:
C21H27N5O6S
Target-Kategorie:
PAI-1|||Others
T69028
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