Aspulvinone H is a natural inhibitor of glutamic oxaloacetate transaminase 1 (GOT1), suppressing glutamine metabolism, making PDAC cells sensitive to oxidative stress and inhibiting cell proliferation, exhibiting potent in vivo antitumor activity in an SW1990-cell-induced xenograft model.
Molekulargewicht:
432.51
CAS Nummer:
[57744-69-1]
Formel:
C27H28O5
Target-Kategorie:
Others
T69068
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