PPI-2458 is a synthetic derivative of fumagillin with antineoplastic and cytotoxic properties. PPI-2458 irreversibly inhibits the enzyme methionine aminopeptidase type 2 (MetAP2), thereby preventing abnormal cell growth and angiogenesis. PPI-2458 is reported to have a better toxicity profile compared to other agents of its class.
Molekulargewicht:
424.53
CAS Nummer:
[431077-35-9]
Formel:
C22H36N2O6
Target-Kategorie:
Others|||Aminopeptidase
T69258
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