(-)-IHCH7041 is a optical rotation negative isomer of IHCH7041. (-)-IHCH7041 is a DRD2 partial agonist. (-)-IHCH7041 showed EC50 = 1.38 nM in Galphai1-gamma9 dissociation and 2.75 nM in beta-arrestin2 recruitment. (-)-IHCH7041 exhibited a inhibition constant (Ki) of 22.44 nM binding affinity at DRD2. (-)-IHCH7041 has antidepressant properties and reverses cognitive impairment.
Molekulargewicht:
409.57
CAS Nummer:
[2813335-07-6]
Formel:
C24H35N5O
Target-Kategorie:
Others
T69513
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