BI-0474 is a potent KRASG12C inhibitor that inhibits GDP-KRAS::SOS1 protein-protein interactions with an IC50 value of 7.0 nM.BI-0474 exhibits significant antiproliferative activity against NCI-H358 cells harboring the G12C mutation, and shows significant anti-tumor activity in a non-small cell lung cancer xenograft model. activity.BI-0474 can be used for cancer research.
Molekulargewicht:
587.74
Reinheit:
>99.99%
CAS Nummer:
[2750570-55-7]
Formel:
C30H37N9O2S
Target-Kategorie:
Kras|||Ras|||Raf
T69529
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten