SRX3212 is a Novel BRD4/PI3Kalpha inhibitor, displaying an IC50 of 3.7 nM toward BRD4BD1 and 32 nM toward BRD4BD2, and therefore was~65-fold more potent inhibitor of BRD4BD1 and~48-fold more potent inhibitor of BRD4BD2 than SF2523 (GLXC-10641), retaining its high inhibitory activity for PI3Kalpha (IC50: 22 nM).
Molekulargewicht:
505.54
CAS Nummer:
[2735720-80-4]
Formel:
C26H23N3O6S
Target-Kategorie:
Others
T69531
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