M-89 MLL inhibitor, CAS [[2446155-01-5]]

Produktübersicht

• Artikelname: M-89 MLL inhibitor, CAS [[2446155-01-5]]
• Artikelnummer: TGM-T69629
• Hersteller Artikelnummer: T69629
• Alternativnummer: TGM-T69629-25MG,TGM-T69629-50MG,TGM-T69629-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

M-89 is a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein-Protein Interaction (Kd = 1.4 nM, IC50 = 25nM). M-89 binds to menin with a Kd value of 1.4 nM and effectively engages cellular menin protein at low nanomolar concentrations. M-89 inhibits cell growth in the MV4,11 and MOLM-13 leukemia cell lines carrying MLL fusion with IC50 values of 25 and 55 nM, respectively, and demonstrates >100-fold selectivity over the HL-60 leukemia cell line lacking MLL fusion.

Produkteigenschaften

• Molekulargewicht: 657.87
• CAS Nummer: [2446155-01-5]
• Formel: C37H47N5O4S
• Target-Kategorie: Others

Bilder

T69629