Camsirubicin, also known as GPX-150, MNPR-201, and CNDO1011, is a synthetic non-cardiotoxic analogue of the anthracycline antibiotic doxorubicin with potential antineoplastic activity. Anthracycline analogue GPX-150 intercalates DNA and impedes the activity of topoisomerase II, inducing single and double-stranded breaks in DNA, inhibiting DNA replication and/or repair, transcription, and protein synthesis, and activating tumor cell apoptosis.
Molekulargewicht:
565.01
CAS Nummer:
[236095-24-2]
Formel:
C27H33ClN2O9
Target-Kategorie:
Others
T69669
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