Cilofexor, also known as GS-9674, is a farnesoid X receptor (FXR) agonist. The nonsteroidal FXR agonist cilofexor (GS-9674) improves markers of cholestasis and liver injury in patients with PSC. In clinical study, cilofexor was well tolerated and led to significant improvements in liver biochemistries and markers of cholestasis in patients with PSC.
Molekulargewicht:
707.99
CAS Nummer:
[2253764-93-9]
Formel:
C32H33Cl3N4O8
Target-Kategorie:
FXR|||Autophagy|||Others
T69724
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