Tofacitinib maleate, CAS [[2052885-67-1]]

Produktübersicht

• Artikelname: Tofacitinib maleate, CAS [[2052885-67-1]]
• Artikelnummer: TGM-T69958
• Hersteller Artikelnummer: T69958
• Alternativnummer: TGM-T69958-25MG,TGM-T69958-50MG,TGM-T69958-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

Tofacitinib maleate, also known as tasocitinib, CP-690550, is a Janus kinase (JAK) inhibitor. Tofacitinib maleate modulates the signaling pathway at the point of JAKs, preventing the phosphorylation and activation of STATs. JAK enzymes transmit cytokine signaling through pairing of JAKs (e.g., JAK1/JAK3, JAK1/JAK2, JAK1/TyK2, JAK2/JAK2). Tofacitinib maleate inhibited the in vitro activities of JAK1/JAK2, JAK1/JAK3, and JAK2/JAK2 combinations with IC50 of 406, 56, and 1377 nM, respectively.

Produkteigenschaften

• Molekulargewicht: 428.449
• CAS Nummer: [2052885-67-1]
• Formel: C16H20N6O.xC4H4O4
• Target-Kategorie: Others

Bilder

T69958