WS-691, CAS [[2035417-32-2]]

Produktübersicht

• Artikelname: WS-691, CAS [[2035417-32-2]]
• Artikelnummer: TGM-T69976
• Hersteller Artikelnummer: T69976
• Alternativnummer: TGM-T69976-25MG,TGM-T69976-50MG,TGM-T69976-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

WS-691 is a highly Potent and Orally Active ABCB1 Modulator. WS-691 significantly increased sensitization of ABCB1-overexpressed SW620/Ad300 cells to paclitaxel (PTX) (IC50 = 22.02 nM). WS-691 significantly increased the intracellular concentration of PTX and [3H]-PTX while decreasing the efflux of [3H]- PTX in SW620/Ad300 cells by inhibiting the efflux function of ABCB1. WS-691 could stabilize ABCB1 by directly binding to ABCB1 WS-691 increased the sensitivity of SW620/Ad300 cells to PTX in vivo without observed toxicity.

Produkteigenschaften

• Molekulargewicht: 405.45
• CAS Nummer: [2035417-32-2]
• Formel: C20H16FN7S
• Target-Kategorie: Others

Bilder

T69976