1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV34) injured by tumor necrosis factor-alpha (TNF-alpha) in a concentration-dependent manner. 3. Ruscogenin significantly attenuate LPS-induced acute lung injury via inhibiting expressions of TF and iNOS and NF-kappa B p65 activation.
Molekulargewicht:
430.62
Reinheit:
99.87%
CAS Nummer:
[472-11-7]
Formel:
C27H42O4
Target-Kategorie:
NOD-like Receptor (NLR)|||NF-kappaB|||NOS
T6S1256
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