Tofacitinib HCl, CAS [[1803005-18-6]]

Artikelnummer: TGM-T70168
Artikelname: Tofacitinib HCl, CAS [[1803005-18-6]]
Artikelnummer: TGM-T70168
Hersteller Artikelnummer: T70168
Alternativnummer: TGM-T70168-25MG,TGM-T70168-50MG,TGM-T70168-100MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Tofacitinib HCl, also known as tasocitinib, CP-690550, is a Janus kinase (JAK) inhibitor. Tofacitinib HCl modulates the signaling pathway at the point of JAKs, preventing the phosphorylation and activation of STATs. JAK enzymes transmit cytokine signaling through pairing of JAKs (e.g., JAK1/JAK3, JAK1/JAK2, JAK1/TyK2, JAK2/JAK2). Tofacitinib HCl inhibited the in vitro activities of JAK1/JAK2, JAK1/JAK3, and JAK2/JAK2 combinations with IC50 of 406, 56, and 1377 nM, respectively.
Molekulargewicht: 348.835
CAS Nummer: [1803005-18-6]
Formel: C16H21ClN6O
Target-Kategorie: Others
T70168