Atrasentan, also known as ABT-627, is a orally available ETA receptor antagonist with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.
Molekulargewicht:
532.61
CAS Nummer:
[178738-96-0]
Formel:
C29H37N2NaO6
Target-Kategorie:
Endothelin Receptor|||Others
T70198
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