Monophosphoryl lipid A (MPLA) is a natural agonist for the toll-like receptor-4 (TLR4). It is useful as an adjuvant in immunization. MPLA is a safe prophylactic agent and has immunotherapeutic applications. It induces tumor necrosis factor and interleukin (IL)-1beta, however not as efficient as lipopolysaccharide (LPS). MPLA improves immune response during bacterial sepsis infection.
Molekulargewicht:
1100.42
CAS Nummer:
[1699735-80-2]
Formel:
C54H106N3O17P
Target-Kategorie:
Others|||TLR
T70268
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