BAY 61-3606 HCl, CAS [[1615197-10-8]]

Produktübersicht

• Artikelname: BAY 61-3606 HCl, CAS [[1615197-10-8]]
• Artikelnummer: TGM-T70377
• Hersteller Artikelnummer: T70377
• Alternativnummer: TGM-T70377-1MG,TGM-T70377-5MG,TGM-T70377-10MG,TGM-T70377-25MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

BAY 61-3606 HCl is a cell-permeable, reversible inhibitor of spleen tyrosine kinase. BAY 61-3606 HCl can inhibit degranulation and block cytokine release from mast cells. Oral administration of BAY 61-3606 to rats was shown to suppress antigen-induced passive cutaneous anaphylactic reaction, bronchoconstriction, and bronchial edema. It can also sensitize MCF-7 breast cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis by inhibiting Cdk9. This compound has been used in a pre-clinical model to explore the feasibility of targeting Syk in the treatment of retinoblastoma.

Produkteigenschaften

• Molekulargewicht: 426.86
• CAS Nummer: [1615197-10-8]
• Formel: C20H19ClN6O3
• Target-Kategorie: Others|||Apoptosis|||Syk

Bilder

T70377