TX-1123 is a potent inhibitor of protein tyrosine kinase (PTK), specifically targeting Src, eEF2-K, PKA, and EGFR-K/PKC. Additionally, it acts as a cyclo-oxygenase (COX) inhibitor, displaying IC50 values of 1.16 µM for COX2 and 15.7 µM for COX1, indicating a higher affinity towards COX2. With low mitochondrial toxicity, TX-1123 is beneficial for cancer research applications.
Molekulargewicht:
312.4
CAS Nummer:
[157397-06-3]
Formel:
C20H24O3
Target-Kategorie:
Others|||COX|||PKA|||PKC|||EGFR|||CaMK|||Src
T70431
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