HM5023507, an orally active dual inhibitor of deltagamma isoforms in immune signaling. HM5023507 inhibited PI3Kdelta and PI3Kgamma isoforms with greater than 100-fold selectivity against PI3Kalpha and PI3Kbeta in recombinant enzymatic assays and in primary human immune cells with an exquisite selectivity against other targets.
Molekulargewicht:
435.87
CAS Nummer:
[1549740-86-4]
Formel:
C21H18ClN7O2
Target-Kategorie:
Others
T70460
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