ACT-672125 is a Potent CXCR3 Antagonist with Therapeutic Potential in Autoimmune Diseases. ACT-672125 showed good physicochemical properties and safety profile. In a proof-of-mechanism model of lung inflammation, ACT-672125 inhibited the recruitment of CXCR3 expressing T cells into the inflamed lung in a dose-dependent manner.
Molekulargewicht:
586.59
CAS Nummer:
[1449367-94-5]
Formel:
C25H25F3N10O2S
Target-Kategorie:
CXCR|||Others
T70616
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