Selonsertib HCl, CAS [[1448428-05-4]]

Artikelnummer: TGM-T70622
Artikelname: Selonsertib HCl, CAS [[1448428-05-4]]
Artikelnummer: TGM-T70622
Hersteller Artikelnummer: T70622
Alternativnummer: TGM-T70622-25MG,TGM-T70622-50MG,TGM-T70622-100MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. GS-4997 targets and binds to the catalytic kinase domain of ASK1 in an ATP-competitive manner, thereby preventing its phosphorylation and activation. GS-4997 prevents the production of inflammatory cytokines, down-regulates the expression of genes involved in fibrosis, suppresses excessive apoptosis and inhibits cellular proliferation.
Molekulargewicht: 481.96
CAS Nummer: [1448428-05-4]
Formel: C24H25ClFN7O
Target-Kategorie: MAPK|||Others|||Apoptosis
T70622