Azalanstat mesylate, CAS [[143484-80-4]]

Artikelnummer: TGM-T70661
Artikelname: Azalanstat mesylate, CAS [[143484-80-4]]
Artikelnummer: TGM-T70661
Hersteller Artikelnummer: T70661
Alternativnummer: TGM-T70661-25MG,TGM-T70661-50MG,TGM-T70661-100MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Azalanstat mesylate is an anti-obesity drug acting as a lanosterol 14alpha-demethylase inhibitor. Azalanstat mesylate has been shown to inhibit cholesterol synthesis in HepG2 cells, human fibroblasts, hamster hepatocytes and hamster liver, by inhibiting the cytochrome P450 enzyme lanosterol 14 alpha-demethylase. When administered orally to hamsters fed regular chow, RS-21607 (50 mg/kg/day) lowered serum cholesterol in a dose-dependent manner (ED50 = 62 mg/kg) in a period of 1 week. It preferentially lowered low density lipoprotein (LDL) cholesterol and apo B relative to high density lipoprotein (HDL) cholesterol and apo A-1.
Molekulargewicht: 526.063
CAS Nummer: [143484-80-4]
Formel: C23H28ClN3O5S2
Target-Kategorie: Others
T70661