PF-05139962, CAS [[1393712-18-9]]

Produktübersicht

• Artikelname: PF-05139962, CAS [[1393712-18-9]]
• Artikelnummer: TGM-T70782
• Hersteller Artikelnummer: T70782
• Alternativnummer: TGM-T70782-25MG,TGM-T70782-50MG,TGM-T70782-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

PF-05139962 is a novel potent mTOR inhibitor with excellent mTOR biochemical inhibition, cellular potency, kinase selectivity and in vitro ADME properties. PF-05139962 has pS473 and pS6 cellular IC50 = 48 and 6 nM respectively. PF-05139962 has great selectivity against other receptors and kinases. No genotoxicity was observed on this compound and no more than 25% inhibiton was observed for major CYP enzymes (3A4, 1A2, 2C9, 2D6) at 3 uM. This compound has LE = 0.35 and LipE up to 6.8 which is in a very desirable range for a kinase inhibitor.

Produkteigenschaften

• Molekulargewicht: 445.54
• CAS Nummer: [1393712-18-9]
• Formel: C21H27N5O4S
• Target-Kategorie: Others

Bilder

T70782