Elenbecestat,also known as E2609 is a BACE1 inhibitor. By inhibiting BACE, a key enzyme in the production of Abeta peptides, E2609 decreases the formation of these peptides which can aggregate into toxic oligomers and protofibrils and eventually form amyloid plaques in the brain. Elenbecestat has been shown to reduce Abeta levels in cerebrospinal fluid, was investigated in two global phase 3 studies in early AD.
Molekulargewicht:
491.41
CAS Nummer:
[1388149-39-0]
Formel:
C19H15F6N5O2S
Target-Kategorie:
Others|||Beta-Secretase
T70800
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten