PF-03671148 is a potent ALK inhibitor. PF-03671148 inhibits the expression of fibrotic genes and protein markers both in vitro in human fibroblasts and in vivo in a rat wound repair model. Wound healing is not inhibited by the topical application of the ALK5 inhibitor to the wound. PF-03671148 may have potential utility for the prevention of dermal scarring.
Molekulargewicht:
317.34
CAS Nummer:
[1378524-25-4]
Formel:
C18H15N5O
Target-Kategorie:
Others
T70826
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