2-Bromo-4-hydroxyacetophenone, CAS [[2491-38-5]]

Artikelnummer: TGM-T7084
Artikelname: 2-Bromo-4-hydroxyacetophenone, CAS [[2491-38-5]]
Artikelnummer: TGM-T7084
Hersteller Artikelnummer: T7084
Alternativnummer: TGM-T7084-1G
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: 4-Hydroxyphenacyl bromide , alpha-Bromo-4-hydroxyacetophenone , PTP Inhibitor I , SHP-1 Inhibitor II
2-Bromo-4-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(deltaSH2)) with a Ki value of 43 µM and PTP1B with a Ki value of 42 µM [1]. SHP-1 and PTP1B both have known roles in regulating insulin signaling as well as myeloid and lymphoid cell differentiation, making inhibitors of these phosphatases of interest in diabetes, cancer, allergy, and inflammation research [2].
Molekulargewicht: 215.04
Reinheit: 99.07%
CAS Nummer: [2491-38-5]
Formel: C8H7BrO2
Target-Kategorie: Phosphatase
T7084