Palifosfamide (tromethamine), a synthetically derived alkylating agent, exhibits potential antineoplastic properties. Acting as the stabilized active metabolite of ifosfamide, it irreversibly alkylates and crosslinks DNA at GC base pairs, inhibiting DNA replication and inducing cell death. Palifosfamide (tromethamine) boasts reduced toxicity in comparison to ifosfamide.
Molekulargewicht:
342.16
CAS Nummer:
[1070409-31-2]
Formel:
C8H22Cl2N3O5P
Target-Kategorie:
Others|||DNA Alkylator/Crosslinker
T71500
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