MF-592, CAS [[1064195-48-7]]

Produktübersicht

• Artikelname: MF-592, CAS [[1064195-48-7]]
• Artikelnummer: TGM-T71510
• Hersteller Artikelnummer: T71510
• Alternativnummer: TGM-T71510-25MG,TGM-T71510-50MG,TGM-T71510-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

MF-592 is a potent and selective antagonists of the EP4 receptor. MF-592 demonstrated good functional potency (hEP4 IC50 = 3 nM) and potent inhibition of PGE2 modulated TNFa release in LPS stimulated human whole blood (hWB) (IC50 = 78nM). In addition, it showed an excellent oral pharmacokinetic (PK) profile and in vivo efficacy in a rat chronic adjuvant-induced-arthritis model (ED50 = 0.1 mg/kg/day).. MF-592 has a desirable overall preclinical profile that suggests it is suitable for further development.

Produkteigenschaften

• Molekulargewicht: 682.61
• CAS Nummer: [1064195-48-7]
• Formel: C34H33Cl2N3O6S
• Target-Kategorie: Others|||Prostaglandin Receptor

Bilder

T71510