KOS-1584, CAS [[1032119-44-0]]

Produktübersicht

• Artikelname: KOS-1584, CAS [[1032119-44-0]]
• Artikelnummer: TGM-T71577
• Hersteller Artikelnummer: T71577
• Alternativnummer: TGM-T71577-25MG,TGM-T71577-50MG,TGM-T71577-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

KOS-1584 is a second-generation epothilone with potential antineoplastic activity. Epothilone KOS-1584 binds to tubulin and induces microtubule polymerization and stabilizes microtubules against depolymerization, which may result in the inhibition of cell division, the induction of G2/M arrest, and apoptosis. Compared to first-generation epothilones, this agent exhibits greater safety and efficacy with an enhanced pharmaceutical profile, including enhanced water solubility and tumor penetration, and reduced CNS exposure. In addition, epothilone KOS-1584 is a poor substrate for the P-glycoprotein (P-gp) drug efflux pump.

Produkteigenschaften

• Molekulargewicht: 489.67
• CAS Nummer: [1032119-44-0]
• Formel: C27H39NO5S
• Target-Kategorie: Others