Pyridostatin (RR82) hydrochloride, a G-quadruplex DNA stabilizing agent (Kd = 490 nM), induces replication- and transcription-dependent DNA damage, promoting growth arrest in human cancer cells. It specifically targets the proto-oncogene Src, leading to reduced SRC protein levels and decreased SRC-dependent cellular motility in human breast cancer cells.
Molekulargewicht:
778.94
CAS Nummer:
[1781882-65-2]
Formel:
C31H37Cl5N8O5
Target-Kategorie:
Others|||DNA/RNA Synthesis
T72201
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten