SARS-CoV-2 Mpro-IN-4 is a dual inhibitor targeting Main Protease (M Pro) and Cathepsin L (CatL), with inhibition concentrations (IC50) of 900 nM and 60 nM, respectively. It effectively blocks SARS-CoV-2 replication in hACE2-expressing A549 cells, demonstrating antiviral activity with an IC50 value of 8.2 nM.
Molekulargewicht:
534.65
Formel:
C30H38N4O5
Target-Kategorie:
SARS-CoV|||Virus Protease|||Others
T72446
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