AChE/BChE/MAO-B-IN-4, an indan-1-one derivative, is a potent inhibitor of monoamine oxidase B (MAO-B) and acetylcholinesterase/butyrylcholinesterase (AChE/BChE). It strongly inhibits human MAO-B with an IC50 of 0.0393 µM and is highly effective against human AChE and BChE with IC50 values of 0.0458 µM and 0.075 µM, respectively. Additionally, this compound exhibits significant antioxidant properties and ability to prevent beta-amyloid plaque aggregation, suggesting its potential in Alzheimers disease (AD) research.
Molekulargewicht:
451.56
Formel:
C26H33N3O4
Target-Kategorie:
Monoamine Oxidase|||Cholinesterase (ChE)|||Others
T72454
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