NOD1/2 antagonist-1 is a dual inhibitor of nucleotide-binding oligomerization domain-like receptors NOD1 and NOD2, exhibiting IC50 values of 1.13 uM for NOD1 and 0.77 uM for NOD2, with an acceptable half-life of 67.6 minutes. NOD1/2 antagonist-1 enhances the antitumor efficacy of paclitaxel and serves as a potent experimental tool for investigating innate immune receptor-mediated signaling and cancer therapy modulation.
Molekulargewicht:
663.03
Reinheit:
99.69%
CAS Nummer:
[2704623-69-6]
Formel:
C32H28ClF5N4O4
Target-Kategorie:
NOD|||NOD-like Receptor (NLR)
T72473
T72473
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