VEGFR-2/BRAF-IN-2, as a dual VEGFR-2 and BRAF kinase inhibitor, exhibits potent IC50 values of 0.111 µM, 0.089 µM, and 0.071 µM against VEGFR-2, BRAF V600E, and BRAF WT, respectively. This compound effectively induces apoptosis and predominantly arrests the cell cycle in the G1 phase.
Molekulargewicht:
608.05
Formel:
C26H21ClF3N5O3S2
Target-Kategorie:
Others|||Apoptosis|||Raf|||VEGFR
T72608
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