c-Met/HDAC-IN-2 is a potent dual inhibitor of c-Met and HDAC, exhibiting IC50 values of 5.40 nM for c-Met and 18.49 nM for HDAC1, respectively. It demonstrates antiproliferative effects on various cancer cell lines, induces G2/M-phase arrest, and triggers apoptosis in HCT-116 cells, making it a promising candidate for anti-cancer resistance research.
Molekulargewicht:
623.66
CAS Nummer:
[2740495-53-6]
Formel:
C34H33N5O7
Target-Kategorie:
c-Met/HGFR|||Apoptosis|||HDAC|||Others
T72759
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