VEGFR-2-IN-30, a compound acting primarily as a VEGFR-2 inhibitor (IC50: 66 nM), demonstrates additional inhibitory effects on PDGFR, EGFR, and FGFR1, with IC50 values of 180, 98, and 82 nM, respectively. It effectively arrests cancer cells in the S-phase and induces both early and late apoptosis.
Molekulargewicht:
607.1
Formel:
C28H23ClN6O4S2
Target-Kategorie:
VEGFR|||Others
T72890
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