TRK/ALK-IN-1 is a potent dual inhibitor of TRK and ALK, exhibiting good correlation between its enzymatic inhibition and anti-proliferative activities, with IC50 values of 2.2 nM for TRKA, 9.3 nM for ALK WT, and 38 nM for ALK L1196M. It holds potential for cancer research applications.
Molekulargewicht:
657.18
Formel:
C31H35ClF2N8O2S
Target-Kategorie:
Trk receptor|||ALK|||Others
T72931
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