G4/HDAC-IN-1, a dual-targeting compound for G4 and HDAC, shows inhibition of intracellular HDAC activity, with an IC50 value of 1.1 µM, and promotes G4 formation. It effectively inhibits proliferation and tumor growth in a TNBC xenograft model, presenting potential for cancer research applications.
Molekulargewicht:
698.27
Formel:
C36H49ClFN7O4
Target-Kategorie:
HDAC|||Others|||DNA/RNA Synthesis
T72946
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