EGFR-IN-61 (compound 22a), a potent EGFR kinase inhibitor, exhibits IC50 values of 42 nM for L858R/T790M, 137 nM for L858R/T790M/C797S, and 743 nM for WT. Additionally, it demonstrates antiproliferative activity against the A549 and H1975 cell lines, with IC50 values of 2.14 µM and 1.82 µM, respectively [1].
Molekulargewicht:
629.15
CAS Nummer:
[2890261-81-9]
Formel:
C33H37ClN8O3
Target-Kategorie:
EGFR
T73128
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
