BMS-986339 is an orally active, potent FXR agonist that engages His298 and ASN287 residues via H-bond formation. It is employed in research on primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and nonalcoholic steatohepatitis (NASH) due to its anti-fibrosis properties.
Molekulargewicht:
643.71
CAS Nummer:
[2477873-64-4]
Formel:
C35H41F4N3O4
Target-Kategorie:
Others|||Cytochromes P450|||FXR
T73155
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