mHTT-IN-1 (Example 1) is a potent inhibitor of the mutant huntingtin protein (mHTT), which is primarily responsible for Huntingtons disease (HD), an inherited autosomal dominant neurodegenerative disorder. This compound effectively reduces mHTT levels with an EC50 of 46 nM.
Molekulargewicht:
381.45
CAS Nummer:
[2839311-21-4]
Formel:
C18H19N7OS
Target-Kategorie:
Huntingtin|||Others
T73289
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