BTK-IN-17 is a selective, orally active inhibitor of Brutons Tyrosine Kinase (BTK) with an inhibition concentration (IC50) value of 13.7 nM. It effectively reduces the expression of phosphorylated BTK at Tyrosine 223 (p-BTK Y223) and phosphorylated Phospholipase C Gamma 2 at Tyrosine 1217 (p-PLCgamma2 Y1217), demonstrating anti-inflammatory properties.
Molekulargewicht:
465.51
Formel:
C26H23N7O2
Target-Kategorie:
Others|||BTK
T73303
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