Erasin is a STAT3 inhibitor (IC50 = 9.7 µM) with higher selectivity for inhibiting STAT3 tyrosine phosphorylation than STAT5 and STAT1. It induces apoptosis in various cancer cell lines (e.g., MDA-MB-231, HCC-827) and is effective against Erlotinib-resistant cancer cells.
Molekulargewicht:
349.38
Formel:
C20H19N3O3
Target-Kategorie:
STAT|||Apoptosis
T73472
T73472
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