CPUL1, a TrxR inhibitor, exhibits proliferation-inhibitory and anti-metastatic effects on A549 cells by modulating epithelial-mesenchymal transition (EMT) through the induction of ROS-mediated ERK/JNK signaling, achieved by inhibiting TrxR1 enzyme activity. The efficacy of CPUL1 is enhanced when used in conjunction with alpha-Lipoic Acid or Dithiodipropionic acid [1].
Molekulargewicht:
434.28
CAS Nummer:
[2043660-80-4]
Formel:
C22H13Cl2N5O
Target-Kategorie:
Others
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