cGAMP (Cyclic GMP-AMPP) diammonium serves as an intrinsic second messenger in metazoans, initiating the production of interferons upon cytosolic DNA detection. It activates the stimulator of interferon genes (STING), subsequently triggering a signaling cascade that culminates in the synthesis of type I interferons and various immune mediators [1] [2] [3] [4].
Molekulargewicht:
708.47
Formel:
C20H30N12O13P2
Target-Kategorie:
Others|||Endogenous Metabolite|||STING
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