Pyridinium bisretinoid A2E (A2E) is a fluorescent chromophore isolated from lipofuscin in retinal pigment epithelium, a lipophilic cation and weak photosensitizer with cytotoxicity. A2E promotes apoptosis under blue light exposure and induces autophagy under photoactivation, damaging membrane integrity in a concentration-dependent manner.
Molekulargewicht:
592.92
Reinheit:
98.19%
CAS Nummer:
[173449-96-2]
Formel:
C42H58NO
Target-Kategorie:
ROS|||Photosensitizer|||Autophagy|||Apoptosis|||Reactive Oxygen Species
T74051
T74051
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