DIZ-3, a selective multimeric G-quadruplex (G4) ligand, employs a G4-ligand-dimerizing approach to intercalate into the G4-G4 interface, thereby stabilizing its higher-order structure. This compound effectively induces cell cycle arrest and apoptosis, inhibiting cell proliferation in cancer cells characterized by alternative lengthening of telomeres (ALT) [1].
Molekulargewicht:
746.89
CAS Nummer:
[2675490-72-7]
Formel:
C46H44F2N8
Target-Kategorie:
DNA/RNA Synthesis|||Others
T74539
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