XL01126, a potent degrader of LRRK2, exhibits DC50 values of 14 nM (G2019S LRRK2) and 32 nM (WT LRRK2), respectively. It has the ability to cross the blood-brain barrier, making it a viable degrader probe for Parkinsons disease research. This compound is instrumental in exploring the non-catalytic and scaffolding functions of LRRK2 [1].
Molekulargewicht:
1019.69
Formel:
C50H64ClFN10O6S2
Target-Kategorie:
PROTACs|||LRRK2
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
