USP28-IN-3 is a highly selective USP28 inhibitor with an IC50 value of 0.1 µM against USP28.USP28-IN-3 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3, and UCHL5.USP28-IN-3 is cytotoxic to human colorectal and lung squamous carcinoma cells, inhibiting c-cells and c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-cells through the ubiquitin-proteasome system. -proteasome system to dose-dependently downregulate cellular levels of c-Myc.
Molekulargewicht:
475.39
Reinheit:
0.9992
CAS Nummer:
[2931509-14-5]
Formel:
C23H20Cl2N2O3S
Target-Kategorie:
DUB
T74793
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